منابع مشابه
Oxygen Sensing and Homeostasis.
The discovery of carotid bodies as sensory receptors for detecting arterial blood oxygen levels, and the identification and elucidation of the roles of hypoxia-inducible factors (HIFs) in oxygen homeostasis have propelled the field of oxygen biology. This review highlights the gas-messenger signaling mechanisms associated with oxygen sensing, as well as transcriptional and non-transcriptional m...
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In this issue of Blood, Jun et al, through the study of neutrophils deficient in the glucose-6-phosphate transporter, describe a novel role for the peroxisome proliferator-activated receptor-γ (PPARG) pathway in the regulation of key neutrophil functions and link this to concomitant hypoxia-inducible factor (HIF) 1α stabilization.
متن کاملOxygen Sensing and Signal Transduction
gy generated through the oxidative metabolism of glucose and fatty acids in the mitochondria, which results in the production of reducing equivalents that are used to maintain an electrochemical gradient that drives ATP synthesis. This highly efficient mechanism for producing ATP is dependent on the utilization of O2 as the terminal electron acceptor at complex IV of the respiratory chain. When...
متن کاملSensing oxygen inside and out
Neuroendocrine cells act as oxygen sensors in animals from fish to humans, but the evolutionary origins of these cells are only just becoming clear.
متن کاملOxygen-binding and sensing proteins
This collection of papers is a snapshot of topics presented at the international conference on Oxygen-Binding and Sensing Proteins (O2BiP) held in Sheffield, UK, on 6 (th)-10 (th) July 2014. The collection will grow over time as new papers relating to O2BiP topics are completed and published.
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 2000
ISSN: 0022-3751,1469-7793
DOI: 10.1111/j.1469-7793.2000.t01-3-00001.x